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饶卫东       

 
办公电话:025-85427635
Office Address:
E-Mail:weidong@njfu.edu.cn
 
个人简况

男,教授,博士生导师。2002年毕业于安徽师范大学化学系获理学学士学位;2005年毕业于苏州大学化学化工学院获理学硕士学位;2010年毕业于新加坡南洋理工大学(Nanyang Technological University)获哲学博士学位(导师Philip Wai Hong Chan);2010年12月至2014年12月在新加坡南洋理工大学从事博士后研究(合作导师:Philip Wai Hong Chan), 2015年1月起任南京林业大学化工学院教授,并入选第五批江苏特聘教授。近年来在Journal of the American Chemical Society, Angewandte Chemie International Edition, Nature Communications, Green Chemistry, Organic Letters, Journal of Organic Chemistry, Advanced Synthesis & Catalysis, Chemistry-A European Journal等国际权威刊物上发表SCI 论文50余篇。

个人荣誉:

2019年校级优秀硕士学位论文指导教师;

2020年校级优秀硕士专业学位论文指导教师;

2020年校级优秀班主任;

2021年校级优秀硕士学位论文指导教师;

2022年校级优秀博士学位论文指导教师;


工作经历

2005.7-2006.6 上海奥博生物医药有限公司,有机合成研究员

2010.12-2014.12月  新加坡南洋理工大学数理学院,博士后

2015.1-至今 南京林业大学 化学工程学院,教授


个人简况

男,教授,博士生导师。2002年毕业于安徽师范大学化学系获理学学士学位;2005年毕业于苏州大学化学化工学院获理学硕士学位;2010年毕业于新加坡南洋理工大学(Nanyang Technological University)获哲学博士学位(导师Philip Wai Hong Chan);2010年12月至2014年12月在新加坡南洋理工大学从事博士后研究(合作导师:Philip Wai Hong Chan), 2015年1月起任南京林业大学化工学院教授,并入选第五批江苏特聘教授。近年来在Journal of the American Chemical Society, Angewandte Chemie International Edition, Nature Communications, Green Chemistry, Organic Letters, Journal of Organic Chemistry, Advanced Synthesis & Catalysis, Chemistry-A European Journal等国际权威刊物上发表SCI 论文50余篇。

个人荣誉:

2019年校级优秀硕士学位论文指导教师;

2020年校级优秀硕士专业学位论文指导教师;

2020年校级优秀班主任;

2021年校级优秀硕士学位论文指导教师;

2022年校级优秀博士学位论文指导教师;


研究方向

过渡金属催化的有机合成方法学;

有机绿色化学;

有机氟化学以及林源性天然产物的结构修饰和改性。


学术成果

39. Dandan Shang, Rui Hu,Qing Bao, Jichao Chen, Lei Yu, Philip Wai Hong Chan* and Weidong Rao*, PtI4-catalyzed oxidative and hydrogenative dearomative [3 + 2] cycloaddition of 1H-indole N-tethered o-alkynylbenzaldehydes, Org. Chem. Front., 2023, 10, 140-149.

38. Chen, J.; R.; Q.; Shang, D.; Yu, L.; Chan, P. W. H.;* Rao, W.* Ligand-controlled chemoselectivity in gold-catalyzed cascade cyclization of 1,4-diene-tethered 2-alkynylbenzaldehydes, Org. Chem. Front., 2022, 9, 6520-6529.

37. Hu, R.; Chen, J.; Wang, Z.; Shang, D.; Yu, L.;Chan, P. W. H.*,Rao, W.* THF-Enabled PtBr2-Catalyzed Desymmetric Hydrogenative [3+2] Cycloaddition of 2-Alkynylbenzaldehyde-Tethered Cyclohexadienones,Organic Chemistry Frontiers, 2022, 9, 3577-3584.

36. Baratay, C. A.; Li, W.; Mathiew, M.; Yu, L.; Kyne, S, H.; Rao, W.*;Chan, P. W. H.* Gold- and Bronsted Acid-Catalysed Deacyloxylative Cycloaromatisation of 1,6-Diyne Esters to 11H-Benzo[a]fluorenes and 13H-Indeno[1,2-1]phenanthrenes, Adv. Synth. Catal. 2022, 364, 1313-1318. 

35. Sang, J.; Feng, L.; Hu, R.; Chen, J.;Shang, D.; Bao, Q.; Rao, W.Sc(OTf)3-Catalyzed C2-Selective Cyanation/Defluorination Cascade of Perfluoroalkylated 3-Indolylmethanols and Application to the Synthesis of 3-Fluoro(perfluoroalkyl)-β-carbolines, Org. Lett. 2021, 23, 7666-7671.

34. An, D.; Sang J.; Hu, R.; Chen, J.; Feng, L.; Rao, W.* Synthesis of 2-Phosphoryl-3-monofluorovinylindoles under Catalyst- and Additive-free Conditions, Adv. Synth. Catal. 2021, 363, 3496-3501.

33. Chen, X.; Rao, W.; Yang, T.;* Koh, M. J.* Alkyl Halides as Both Hydride and Alkyl Sources in Catalytic Regioselective Reductive Olefin Hydroalkylation, Nature Commun. 2020, 11, 5857.

32. Yang, T.; Chen, X.; Rao, W.; Koh, M. J. Broadly Applicable Directed Catalytic Reductive Difunctionalization of Alkenyl Carbonyl Compounds, Chem 20206, 738-751.

31. An, D.; Miao, X.; Ling, X.; Chen, X.; Rao, W.* DBSA-Catalyzed Regioselective Dehydrative Friedel-Crafts Arylation of CF3-Containing 3-Indolyl(2-thiophenyl)methanols with 2-Substituted Indoles in Water, Adv. Synth. Catal. 2020, 362, 1514-1524.

30. Chen, X.; Zhou, Y.; Jin, J.; Farshadfar, K.; Ariafard, A.*; Rao, W.*; Chan, P. W. H.* Gold Catalyzed Cyclopropanation/[5+3] Cycloaddition of 1,4,9-and 1,4,10-Allenenynes to Bicyclo[3.3.1]nonane Derivatives, Adv. Synth. Catal. 2020, 362, 1084-1095.

29. Zhong, J.; Hu, R.; Sang, J.; Rao, W.* Gold(I)-Catalyzed Intramolecular [4+2] Cycloaddition of ortho-(N-tethered 1,6-diynyl)benzaldehydes to 3,4-dihydrobenzo[f]isoquinolin-1(2H)-onesTetrahedron Lett. 2020, 61, 152200.

28. Chen, X.;# Ling, X.;# An, D.; Rao, W.* Gold-Catalyzed Sequential Cycloisomerization of 1,3,9-Ene-allene-ynes to Fused Spirocarbocycles. Eur. J. Org. Chem. 2020, 32, 5227-5233.

27. Zhou, Y.; Chen, X.; Ling, X.; Rao, W.* Catalyst- and additive-free Baeyer-Villiger-type oxidation of α-iodocyclopentenones to α-pyrones: using air as the oxidant, Green Chem. 2019, 21, 5611-5615.

26. Ling, Y.; An, D.; Zhou, Y.; Rao, W.* Ga(OTf)3-catalyzed temperature-controlled regioselective Friedel-Crafts alkylation of trifluoromethylated 3-indolylmethanols with 2-substituted indoles: divergent synthesis of trifluoromethylated unsymmetrical 3,3′-and 3,6′-bis(indolyl)methanes, Org. Lett. 2019, 21, 3396-3401.

25. Zhou, Y.; Chen, X.; Yin, D.; Ling, Y.; Wang, S.; Zhang, X.; Rao, W.* Gold-catalyzed cycloisomerization/halogenation sequence of 1,3-enyne esters with NXS: efficient synthesis of 5-bromo/iodo cyclopentenones, Eur. J. Org. Chem., 2019, 999-1007.

24. Chen, X.; Zhou, Y.; Hong, M.; Ling, Y.; Yin, D.; Wang, S.; ZhangX.;* Rao, W.* Gold(I)-catalyzed tandem cycloisomerization and fluorination of 1,3(4)-enyne esters with NFSI: one-pot assembly of 5-fluoro-cyclopentenones, Adv. Synth. Catal. 2018360, 3700-3708.

23. Chen, C.; Chen, X.; Zhang, X.; Wang, S.; Rao, W.;* Chan, P. W. H.* Gold-catalyzed dehydrogenative cycloisomerization of 1,4-enyne esters to 3,5-disubstituted phenol derivatives, Adv. Synth. Catal. 2017, 359, 4359-4368.

22. Zou, Y.; Chen, C.; Chen, X.; Zhang, X.;* Rao, W.* Silica gel mediated Friedel-Crafts alkylation of 3-indolylmethanols with indoles: synthesis of unsymmetrical bis(3-in-dolyl)methanes, Eur.J.Org.Chem. 201716, 2266-2271.

21. Zhang, X.;*Li, P.; Lyu, C.; Yong, W.; Li, J.; Pan, X.; Zhu, X.; Rao, W.Palladium-catalyzed one-pot synthesis of via 1H-indole-3-sulfonates generated in situ from 2-alkynyl arylazides and sulfonic acids ” Adv. Synth. Catal. 2017, 359, 4147-4152.

20. Zhang, X.;* Li, P.; Lyu, C.; Yong, W.; Li, J.; Zhu, X.; Rao, W* Synthesis of 1H-indole-3-sulfonates via palladium-catalyzed tandem reactions of 2-alkynyl arylazides with sulfonic acids, Org. Biomol. Chem. 201715, 6080-6083.

19. Chen, C.; Zou, Y.; Chen, X.; Zhang, X.; Rao, W.;* Chan, P. W. H. * Gold-catalyzed tandem 1,3-migration/double cyclopropanation of 1-ene-4,n-diyne esters to tetracyclodecene and tetracycloundecene derivatives, Org. Lett. 2016, 18, 4730-4733.

18. Rao, W.;* Boyle, J. W.; Chan, P. W. H.*, Gold-catalyzed sequential cyclization of 1-en-3,9-Diyne esters to partially hydrogenated 3H-dicyclopenta[a,b]naphthalenesChem. Eur. J. 2016, 22, 6532-6536.

17. Zhang, X.;* Sun, X.; Fan, H.; Lyu, C.; Li, P.; Zhang, H.; Rao, W.*.Gold-catalyzed formation of indole derivatives from 2-alkynyl arylazides and oxygen-containing heterocyclesRSC Adv. 20166, 56319-56322.

16. Zhang, X.;* Sun, X.; Fan, H.; Li, P.; Lyu, C.; Rao, W.* Gold-catalyzed chemoselective synthesis of heterocycles from3-(2-azidophenyl)prop-2-yn-1-ols and aldehydes, Eur. J. Org. Chem. 2016, 4265-4268.

15. Rao, W.; Susanti, D.; Ayers, B. J.; Chan, P. W. H.* Ligand-controlled product selectivity in Gold-catalyzed double cycloisomerization of 1,11-dien-3,9-diyne benzoates, J. Am. Chem. Soc. 2015, 137, 6350-6355.

14. Rao, W.; Sally, Berry, S. N.; Chan, P. W. H.* Gold-catalyzed cycloisomerization of 1,6,8-dienyne carbonates and esters to cis-cyclohepta-4,8-diene-fused pyrrolidines, Chem. Eur. J. 2014, 20, 13174-13180.

13. Rao, W.; Chan, P. W. H.* Gold-catalyzed [2+2+1] cycloaddition of 1,6-diyne carbonates and esters with aldehydes to 4-(cyclohexa-1,3-dienyl)-1,3-dioxolanes, Chem. Eur. J. 2014, 20, 713-718.

12. Rao, W.; Koh, M. J.; Li, D.; Hirao, H.;* Chan, P. W. H.* Gold-catalyzed cycloisomerization of 1,6-diyne carbonates and esters to 2,4a-dihydro-1H-fluorenes, J. Am. Chem. Soc. 2013, 135, 7926-7932.

11. Rao, W.; Sally, Koh, M. J.; Chan, P. W. H.* Gold-catalyzed cycloisomerization of 1,7-enyne esters to structurally diverse cis-1,2,3,6-tetrahydropyridin-4-yl ketones, J. Org. Chem. 201378, 3183-3195.

10. Rao, W.; Koh, M. J.; Kothandaraman, P.; Chan, P. W. H.* Gold-catalyzed cycloisomerization of 1,7-diyne benzoates to indeno[1,2-c]azepines and azabicyclo[4.2.0]octa-1(8),5-dines, J. Am. Chem. Soc. 2012, 134, 10811-10814.

9. Rao, W.; Susanti, D.; Chan, P. W. H.* Gold-Catalyzed Tandem 1,3-Migration/[2+2] Cycloaddition of 1,7-Enyne Benzoates to Azabicyclo[4.2.0]oct-5-enes, J. Am. Chem. Soc. 2011, 133, 15248-15251.

8. Kothandaraman, P.; Rao, W.; Foo, S. J.; Chan, P. W. H.* Gold-catalyzed cycloisomerization reactions of 2-tosylaminophenylprop-1-yn-3-ols as a versatile approach for indole synthesis, Angew. Chem. Int. Ed. 201049, 4619-4623.

7. Rao, W.; Kothandaraman, P.; Koh, C. B.; Chan, P. W. H.* Copper(II) Triflate Catalyzed Intramolecular Hydroamination of Homoallylic Aminoalcohols as an  Expedient Route to Trans-2,5-Dihydro-1H-pyrroles and 1,2-Dihydroquinolines, Adv. Synth. Catal. 2010, 352, 2521-2530.

6. Rao, W.; Chan, P. W. H.* Unexpected Iron(III) Chloride-Catalysed Dimerisation of 1,1,3-Trisubstituted-prop-2-yn-1-ols as an Expedient Route to Highly Conjugated Indenes, Org. Biomol. Chem. 201084016-4025.

5. Rao, W.; Zhang, X.; Sze, E. M. L. Chan, P. W. H.*Ytterbium(III) Triflate-Catalyzed Amination of 1-Cyclopropylprop-2-yn-1-ols as an Expedient  Route to Conjugated Enynes, J. Org. Chem. 200974, 1740-1743.

4. Rao, W.; Chan, P. W. H.*Gold- and Silver-Catalyzed Tandem Amination/Ring Expansion of Cyclopropylmethanols with Sulfonamides as an Expedient Route to Pyrrolidines, Chem. Eur. J. 2008, 14, 10486-10495.

3. Rao, W.; Chan, P. W. H.* Gold-Catalysed Allylic Alkylation of Aromatic and Heteroaromatic Compounds with Allylic Alcohols, Org. Biomol. Chem. 200862426-2433.

2. Rao, W.;  Tay, A. H. L.; Goh, P. J.; Choy, J. M. L.; Ke, J. K.; Chan, P. W. H.* Iodine-Catalyzed Allylation of 1,3-Dicarbonyl Compounds with Allylic Alcohols at Room Temperature, Tetrahedron Lett. 200849, 122-126.

1. Rao, W.; Chan, P. W. H.* Stereoselective Synthesis of Trans-a-ketohydrazones from Silyl Enol Ethers Mediated by Iodobenzene Diacetate, Tetrahedron Lett. 200748, 3789-3792.

授权发明专利:

13.饶卫东、胡睿、王泽梁、陈继超,一种苯环稠合的5/6/7/6四环化合物及其合成方法,ZL 202210188887.6。

12.饶卫东、桑静静、商丹丹、包晴、冯丽一种3-氟-β-咔啉化合物及其合成方法和应用,ZL202111012417.6。

11.饶卫东、桑静静、冯丽、商丹丹、胡睿, 一种含三氟甲基全碳季碳中心吲哚乙腈化合物及其制备方法和应用,ZL202111012404.9。

10.饶卫东、安镝、桑静静、胡睿、陈继超、冯丽, 一种2-膦酰基-3-氟代乙烯基吲哚化合物及其制备方法,ZL202110013538.6。

9.饶卫东、安镝、桑静静、冯丽、胡睿, 一种水相合成含三氟甲基C-2膦酰基吲哚化合物的方法,ZL202110149405.1。

8.饶卫东、周媛媛、凌媛、尹栋梁、钟建凯、陈先枭,一种1-乙烯基-4 ,5-二氢吡咯[1 ,2-a]喹喔啉化合物的合成方法,ZL201811130849.5。

7.饶卫东、周劭诺、周媛媛,一种合成新型α-溴代环戊烯酮的法,ZL201811127378.2。

6.饶卫东、陈翠丽、周媛媛、陈先枭、凌媛、尹栋梁,一种新型5-烯丙基环戊烯酮的制备方法及其产品,ZL 201810440839.5。

5.饶卫东、陈先枭、周媛媛、尹栋梁、凌媛,一种新型氟代环戊烯酮的制备方法及其产品,ZL201810311475.0。

4.饶卫东、周劭诺、周媛媛,一种合成α-碘代环戊烯酮类化合物的方法, ZL201811127426.8。

3.饶卫东、安镝、胡睿、桑静静、凌想想,一种水相合成含三氟甲基噻吩基非对称双吲哚化合物的新方法,ZL201910951670.4。

2.饶卫东、周媛媛、凌想想、安镝、陈先枭,一种α-吡喃酮类化合物的绿色合成方法,ZL201910546421.7。

1.饶卫东、凌媛、安镝、凌想想、周媛媛,一种含三氟甲基3,6’-非对称双吲哚化合物及其合成方法, ZL201811407604.2。









课程名称、上课时间地点

本科生课程:

天然产物化学

研究生课程:

有机化合物波谱分析

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